波多野结衣乳巨码无在线观看-久久久久久久av-久热精品在线-超碰美女-污视频大全-91极品身材尤物theporn-五月天婷婷网站-国产精品九九九九-色九月婷婷-黑白配av-香港三级日本三级韩国三级-亚洲成人av网址-日韩精品一区二区三区视频-www.av欧美-国产情侣av在线-日韩在线一二三-黄色片特级-在线观看自拍-91在线观看欧美日韩-四虎免费久久

當前位置:
首頁 > 技術文章 > 黃連堿 性能特點
目錄導航 Directory
服務熱線
技術支持Article
黃連堿 性能特點
點擊次數:76 更新時間:2026-09-07

黃連堿

分析標準品,HPLC≥98%

Coptisine

CAS號:3486-66-6

分子式:C19H14NO4+

分子量:320.32

MDLMFCD03792689

貨號

規格/參數/品牌

價格

貨期

YJ-B20560-10mg

分析標準品,HPLC≥98%

550.00

現貨

YJ-B20560-20mg

分析標準品,HPLC≥98%

850.00

現貨

 

產品介紹

熔點:212-217 ℃

外觀:淺黃色針狀結晶 (乙醇)

溶解性:極略微溶于水,微溶于乙醇,溶于堿

儲存條件:2-8℃

注意:部分產品我司僅能提供部分信息,我司不保證所提供信息的權威性,僅供客戶參考交流研究之用。

參考文獻(60)

60. [IF=6.7] Mingzhu Qi et al."Qingxin Jieyu Granule alleviates myocardial infarction through inhibiting neutrophil extracellular traps via activating ANXA1/FPR2 axis."PHYTOMEDICINE.2024 Dec;135:156147

59. [IF=4.1] Yufeng Huang et al."Study on the correlation between alkaloids and tastes of Coptis Rhizome from four species based on UHPLC-QQQ-MS/MS combined with electronic tongue technique."Frontiers in Plant Science.2024 Nov;15:

58. [IF=3.1] Qian Chunmei et al."Coptisine inhibits esophageal carcinoma growth by modulating pyroptosis via inhibition of HGF/c-Met signaling."NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY.2025 Jan;:1-15

57. [IF=1.8] Panpan Wang et al."In vivo and in vitro chemical composition and biological activity of traditional vs. dispensing granule decoctions of Coptidis Rhizoma: A comparative study."BIOMEDICAL CHROMATOGRAPHY.2024 Jul;:e5960

56. [IF=4.1] Huaixin Liu et al."A magnetic beads-based ligand fishing method for rapid discovery of monoterpene indoles as monoamine oxidase A inhibitors from Hunteria zeylanica."JOURNAL OF CHROMATOGRAPHY A".2024 May;1722:464896

55. [IF=4.9] Xueyu Pu et al."Lipids Extracted from Mycobacterial Membrane and Enveloped PLGA Nanoparticles for Encapsulating Antibacterial Drugs Elicit Synergistic Antimicrobial Response against Mycobacteria."MOLECULAR PHARMACEUTICS".2024;21(5):2238–2249

54. [IF=5.4] Sihao Zhang et al."Chang-Kang-Fang alleviates diarrhea predominant irritable bowel syndrome (IBS-D) through inhibiting TLR4/NF-κB/NLRP3 pathway."JOURNAL OF ETHNOPHARMACOLOGY".2024 Apr;:118236

53. [IF=5.4] Wenjuan Ma et al."Uncovering the key pharmacodynamic material basis and possible molecular mechanism of Xiaoke formulation improve insulin resistant through a comprehensive investigation."JOURNAL OF ETHNOPHARMACOLOGY.2024 Apr;323:117752

52. [IF=7.9] Shan Zhang et al."Enhancing β-Cell Function and Identity in type 2 diabetes: The Protective Role of Coptis deltoidea C. Y. Cheng et Hsiao via Glucose Metabolism Modulation and AMPK Signaling Activation."PHYTOMEDICINE.2024 Jan;:155396

51. [IF=2.9] Qi Ying et al."Sanhuang Xiexin Decoction Ameliorates TNBC By Modulating JAK2-STAT3 and Lipid Metabolism."Chinese Journal of Integrative Medicine.2023 Nov;:1-10

50. [IF=7.9] Min Zhao et al."N6-methyladenosine modification of TSC1 mRNA contributes to macrophage polarization regulated by Coptisine in DSS-induced ulcerative colitis."PHYTOMEDICINE.2023 Oct;:155153

49. [IF=4.6] Fengge YANG et al."Deciphering chemical and metabolite profiling of Chang-Kang-Fang by UPLC-Q-TOF-MS/MS and its potential active components identification."Chinese Journal of Natural Medicines.2023 Jun;21:459

48. [IF=7.9] Jiangna Yan et al."Blocking LTB4 Signaling-mediated TAMs Recruitment by Rhizoma Coptidis Sensitizes Lung Cancer to Immunotherapy."PHYTOMEDICINE.2023 Jul;:154968

47. [IF=6.5] Wei Liu et al."Genome-wide analysis of bHLH gene family in Coptis chinensis provides insights into the regulatory role in benzylisoquinoline alkaloid biosynthesis."PLANT PHYSIOLOGY AND BIOCHEMISTRY.2023 Aug;201:107846

46. [IF=3.571] Ning Zhou et al."Exploring the efficacy mechanism and material basis of three processed Coptidis Rhizoma via metabolomics strategy."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.2023 Aug;232:115450

45. [IF=6.656] Ning Zhou et al."Characterizing the specific mechanism of series processed Coptidis Rhizoma by multi-organ metabolomics combined with network pharmacology and molecular docking."PHYTOMEDICINE.2023 Jun;114:154804

44. [IF=3.614] Vinay Naithani et al."Preparation of open tubular capillary column covalently coated with polystyrene sulfonate with 4,4′-Azobis(4-cyanopentanoyl chloride) as polymerization initiator for electrochromatographic separation of alkaloids, sulfonamides, and p

43. [IF=0] Xiaoming Yin et al."Assessment of alkaloids from the stems of 14 Berberis species in China."Separation Science Plus.2022 Dec;:202200114

42. [IF=7.419] Yanlu Liu et al."Coptisine protects against hyperuricemic nephropathy through alleviating inflammation, oxidative stress and mitochondrial apoptosis via PI3K/Akt signaling pathway."BIOMEDICINE & PHARMACOTHERAPY.2022 Dec;156:113941

41. [IF=3.024] Xuan Yu et al."An innovative extraction strategy for herbal medicine by adopting p-sulphonatocalix[6]/[8]arenes."PHYTOCHEMICAL ANALYSIS

40. [IF=6.656] Ye Yang et al."Coptis chinensis polysaccharides dynamically influence the paracellular absorption pathway in the small intestine by modulating the intestinal mucosal immunity microenvironment."PHYTOMEDICINE.2022 Sep;104:154322

39. [IF=1.345] Ya-Li  Zhang et al."Coptisine suppresses proliferation and inhibits metastasis in human pancreatic cancer PANC-1 cells."J Asian Nat Prod Res. 2020;22(5):452-463

38. [IF=3.004] Kai Zhang et al."Untargeted metabolomics reveals the synergistic mechanisms of Yuanhu Zhitong oral liquid in the treatment of primary dysmenorrhea."J Chromatogr B. 2021 Feb;1165:122523

37. [IF=3.463] Xiao-Meng Liu et al."Comparative transcriptome analysis provides novel insights into the molecular mechanism of berberine biosynthesis in Coptis chinensis."Sci Hortic-Amsterdam. 2022 Jan;291:110585

36. [IF=3.935] Meng Chen et al."Comprehensive analysis of Huanglian Jiedu decoction: Revealing the presence of a self-assembled phytochemical complex in its naturally-occurring precipitate."J Pharmaceut Biomed. 2021 Feb;195:113820

35. [IF=3.935] Yang Song et al."Pharmacokinetics, tissue distribution and plasma protein binding rate of palmatine following intragastric and intravenous administration in rats using liquid chromatography tandem mass spectrometry."J Pharmaceut Biomed. 2021 Sep;203:11422

34. [IF=3.963] Zhong-min Zhao et al."Anti-phytopathogenic activity and the possible mechanisms of action of isoquinoline alkaloid sanguinarine."Pestic Biochem Phys. 2019 Sep;159:51

33. [IF=4.845] Xiaohong Zhang et al."Laboratory bioassay, greenhouse experiment and 3D-QSAR studies on berberine analogues: a search for new herbicides based on natural products."Pest Manag Sci. 2021 Apr;77(4):2054-2067

32. [IF=5.81] Zhao  Jing et al."Intra-Herb Interactions: Primary Metabolites in Coptidis Rhizoma Extract Improved the Pharmacokinetics of Oral Berberine Hydrochloride in Mice."Front Pharmacol. 2021 Jun;0:1426

31. [IF=6.023] Maiquan Li et al."Discovery of Keap1?Nrf2 small?molecule inhibitors from phytochemicals based on molecular docking."Food Chem Toxicol. 2019 Nov;133:110758

30. [IF=6.4] Jing Zhao et al."Natural Nano-Drug Delivery System in Coptidis Rhizoma Extract with Modified Berberine Hydrochloride Pharmacokinetics."Int J Nanomed. 2021; 16: 6297–6311

29. [IF=1.618] Yang Yanfang et al."Determination of Alkaloid Contents in Various Tissues of Coptis Chinensis Franch. by Reversed Phase-High Performance Liquid Chromatography and Ultraviolet Spectrophotometry."J Chromatogr Sci. 2017 May;55(5):556-563

28. [IF=1.618] Li Jiang-Yan et al."Seasonal Variation of Alkaloid Contents and Anti-Inflammatory Activity of Rhizoma coptidis Based on Fingerprints Combined with Chemometrics Methods."J Chromatogr Sci. 2015 Aug;53(7):1131-1139

27. [IF=2.795] Yue  Xiao et al."Berberine activates bitter taste responses of enteroendocrine STC-1 cells."Mol Cell Biochem. 2018 Oct;447(1):21-32

26. [IF=3.197] Bingxin Ma et al."Coptis chinensis inflorescence ameliorates hyperglycaemia in 3T3-L1 preadipocyte and streptozotocin-induced diabetic mice."J Funct Foods. 2016 Mar;21:455

25. [IF=3.396] Liang  Jie et al."Expression and functional activity of bitter taste receptors in primary renal tubular epithelial cells and M-1 cells."Mol Cell Biochem. 2017 Apr;428(1):193-202

24. [IF=3.935] Ka-Yan Kwok et al."Quality evaluation of commercial Huang-Lian-Jie-Du-Tang based on simultaneous determination of fourteen major chemical constituents using high performance liquid chromatography."J Pharmaceut Biomed. 2013 Nov;85:239

23. [IF=4.759] Lvhuan Wang et al."Online screening of acetylcholinesterase inhibitors in natural products using monolith-based immobilized capillary enzyme reactors combined with liquid chromatography-mass spectrometry."J Chromatogr A. 2018 Aug;1563:135

22. [IF=6.023] Ling Zhu et al."Coptis chinensis inflorescence extract protection against ultraviolet-B-induced phototoxicity, and HPLC–MS analysis of its chemical composition."Food Chem Toxicol. 2012 Jul;50:2584

21.  Chen, Meng, et al. "Comprehensive analysis of Huanglian Jiedu decoction: Revealing the presence of a self-assembled phytochemical complex in its naturally-occurring precipitate." Journal of Pharmaceutical and Biomedical Analysis 195 (2021): 113820.https:##

20.  Yue, Xiao, et al. "Berberine activates bitter taste responses of enteroendocrine STC-1 cells." Molecular and cellular biochemistry 447.1 (2018): 21-32.https:##doi.org/10.1007/s11010-018-3290-3

19.  Ma, Bingxin, et al. "Coptis chinensis inflorescence ameliorates hyperglycaemia in 3T3-L1 preadipocyte and streptozotocin-induced diabetic mice." Journal of Functional Foods 21 (2016): 455-462.https:##doi.org/10.1016/j.jff.2015.12.021

18.  Liang, Jie, et al. "Expression and functional activity of bitter taste receptors in primary renal tubular epithelial cells and M-1 cells." Molecular and cellular biochemistry 428.1-2 (2017): 193-202.https:##doi.org/10.1007/s11010-016-2929-1

17.  Yang, Yanfang, et al. "Determination of alkaloid contents in various tissues of Coptis chinensis Franch. by reversed phase-high performance liquid chromatography and ultraviolet spectrophotometry." Journal of chromatographic science 55.5 (2017): 556-563. h

16.  Zhu, Ling, et al. "Coptis chinensis inflorescence extract protection against ultraviolet-B-induced phototoxicity, and HPLC–MS analysis of its chemical composition." Food and chemical toxicology 50.7 (2012): 2584-2588.https:##doi.org/10.1016/j.fct.2012.04.0

15.  康念欣,袁炎炎,張瀟,路穎慧,李晴霞,李飛,譚鵬.酒黃連HPLC特征圖譜的建立及聚類分析和主成分分析[J].世界科學技術-中醫藥現代化,2020,22(08):2790-2798.

14.  紀萬里,周澤華,王婷婷,安叡,梁琨,王新宏.基于UPLC-LTQ-Orbitrap-MS方法分析半夏瀉心湯化學成分[J].藥物分析雜志,2020,40(10):1736-1750.

13.  王盼,儲全根,軒云,蔡正銀.抵當陷胸湯HPLC-MS指紋圖譜研究[J].時珍國醫國藥,2020,31(12):2937-2940.

12.  李聽弦  李蒙  張志 等. 一測多評法測定不同味連飲片中6個生物堿類成分的含量[J]. 藥物分析雜志  2018  038(007):1132-1138.

11.  張瀟, 張亞麗, 苗祥貞,. 黃連不同炮制品及組分的抗腫瘤活性與6種生物堿含量相關性研究[J]. 中華中醫藥雜志, 2019, v.34(06):350-353.

10.  趙露, 江健梅, 孟琦,. 白屈菜生育期內生物堿含量的變化規律[J]. 吉林農業大學學報, 2017(5):590-595.

9.  米佳, 賀文達, 梁心怡,. 黃連肉桂藥對指紋圖譜的聚類分析及多指標的定量分析[J]. 時珍國醫國藥, 2019, 30(01):83-86.

8.  皮文霞  朱鑫仙  方婷 等. HPLC同時測定"三熱論"方各純化部位中藥根堿、表小檗堿、黃連堿、巴馬汀和小檗堿的含量[J]. 中國實驗方劑學雜志  2012  18(14):110-113.

7.  李聽弦, 李蒙, 張志,. 基于高效液相色譜指紋圖譜及紅外光譜評價黃連及其炮制品質量差異[J]. 中南藥學, 2019, 017(004):556-560.

6.  曹一佳  曲玉霞  孫雨 等. UPLC-MS/MS法同時測定砂連和胃膠囊中10種化合物含量[J]. 國際藥學研究雜志  2020  v.47(01):76-81.

5.  房康, 吳高榮, 王輝,. 黃連解毒湯自沉淀化學成分及其抗PC12細胞損傷研究[J]. 中草藥, 2017(18).

4.  柳鑫,楊艷芳,宋紅萍,張小波,黃璐琦,吳和珍.基于MaxEntArcGIS的黃連生長適宜性區劃研究[J].中國中藥雜志,2016,41(17):3186-3193.

3.  李文芳  王曉明  潘桂湘 等. LC-MS/MS測定養血清腦顆粒中15個生物堿成分的含量[J]. 遼寧中醫雜志  2017(10):134-136+229.

2.  尚嬋 李孟璇 李海波 何亮偉 孟兆青 黃文哲 王振中 丁崗 楊中林 蕭偉.LC-MS/MS同時測定痛安注射液中13個成分的含量[J].中國中藥雜志 2017 42(10):1901-1907.

1.  王永占 沈勇 史曉倩 韓玙 楊生超 梁艷麗 謝世清.HPLC法同時測定云黃連中四種生物堿的含量[J].中國藥師 2013 16(07):947-949.

2011年開始我們致力于在生命科學領域生物醫學實驗技術及論文潤色服務,協助客戶各類實驗服務及論文潤色十多年,是您值得信賴的科研合作伙伴!

如果您受時間、試驗條件等限制而無法完成您的課題研究,歡迎您與我們聯系。

 

實驗技術服務:

 


滬公網安備 31011802001676號